MadWorld

Three days prior to the events in the game, the fictional Varrigan City had become a target for a group of terrorists known as "The Organizers", who severed the island city's transportation and communication ties with the rest of the world, and then released a virus onto its population that would kill them in less than 24 hours. However, the Organizers informed the populace that any person that killed another would receive the vaccine. The city was quickly transformed into the stage of a recurring game show called "DeathWatch", with announcers Howard "Buckshot" Holmes (Greg Proops) and former DeathWatch fighter Kreese Kreeley (John DiMaggio). The remaining citizens of Varrigan City as well as new hopefuls become the show's contestants, hoping to become the top-ranked fighter in the game and win a large cash prize.